Patients suffering from genetic disorders such as lupus or hemolytic disorders such as anemia also are most likely to have a lower MPV reading than normal.test low, mpv test, corpuscular volume mcv, complete blood count cbc. Created for people with ongoing healthcare needs but benefits everyone. When a person has a low red blood count and low hemoglobin levels, their body has to work harder to get enough oxygen to other. Keys: mchc blood test, mchc blood test low, mch high, mch blood test, mpv blood. MPV: MPV value is of no concern if your Hgb & WBC counts are normal. Excessive bleeding is the most common problem encountered by patients who suffer from thrombocytopenia since their platelet count is very low which makes it difficult for their blood to clot quickly. A low red blood count can cause feelings of fatigue and weakness. You would also need the data from at least a CBC (Complete Blood Count - which usually includes a platelet count and MPV) with WBC (white blood cell). Low monocytes in a blood test result may be accompanied by unexplained weight loss. Because leukemia can also cause low platelet count, easy bleeding is often a sign. Thrombocytopenia is usually the culprit in cases where the patients have an extraordinarily low level of MPV especially if it has resulted from aplastic anemia which impairs the production of the platelets in the body. The journal Mayo Clinic Proceeding reports that monocytopenia (low monocyte count) is a feature of some types of leukemia.The use of a drug like heparin, which lowers your platelet count or an overactive spleen are other reasons that can account for a low MPV reading.Usually a low MPV is associated with viral infections among which AIDS is the most prominent one.2a), while the 5-year DSS rates were 20.5 and 62.2 in the MPV low and MPV high groups, respectively (P 0.0031 Fig. The 5-year OS rate was significantly lower in the MPV low compared with the MPV high group (16.9 vs. Learn more about laboratory tests, reference ranges, and understanding results. We then determined the prognostic significance of MPV. Besides this, a low MPV is also considered a symptom of many other diseases and disorders. A low MPV test result may be a sign of: Certain cancers Side effects from certain medicines Aplastic anemia Autoimmune diseases Bacterial or viral infections Genetic conditions Alcohol use disorder (AUD) To learn what your results mean, talk with your provider. Having a Low MPV indicates that the platelet count in your blood is lower than normal and that you are in danger of suffering more blood loss in case you get injured. It can provide the doctors with the knowledge of whether the body is generating more platelets than normal since the size of the platelet becomes enlarged in such circumstances. The use of this reading is made in determining the rate of production of platelets in patients who are suffering from problems or diseases related to platelet destruction or bone marrow. CBC or Complete Blood Profile is the test in which the calculation of this reading is usually included.
It is a reading which represents the size of the platelets in a blood sample and is determined by a machine. In a person who has no history of bleeding and a normal platelet count, an abnormal PMV is of less clinical usefulness.MPV is the abbreviated form of Mean Platelet Volume. However, thrombocytopenia associated with a low MPV is more consistent with the suppression of cell production by the bone marrow (aplastic anemia or congenital abnormality).Ī high MPV seems to be associated with a cardiovascular risk and an increased risk of thrombosis (phlebitis, etc.). Although a bone marrow disorder cannot be ruled out (congenital abnormalities, myelodysplastic syndromes), causes not involving the bone marrow are common (inflammatory or autoimmune diseases that destroy platelets). In a patient with thrombocytopenia (below normal platelet count), a high MPV suggests that the bone marrow is compensating by producing new platelets. 008) and platelet count was significantly lower in the GAD. MPV results are interpreted in light of not only the platelet count, but also other clinical data and the blood count. According to the comparison of complete blood count values, MPV was significantly higher (p. There are three main types of cells circulating in your bloodstream white blood cells, red blood cells, and platelets. The total platelet mass (combination of platelet count and size) is controlled, and the mean platelet volume tends to be higher when the platelet count is lower. Platelets with a higher volume are more active. MPV is an indicator of the size of the platelets, whose function is to clot blood.
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